000			01459nam a2200265Ia 4500
008			220216s9999 xx 000 0 und d
100			_aLam K L
245		0	_aSusceptibility of human B lymphocyte cell lines to dialysed latex B- and C- sera fractions
260			_bJournal of Rubber Research _c2012
300			_a187-195
500			_aSource Year: 2012
520			_aHevea brasiliensis latex sera are being investigated for anticancer property. In the present cell based assay, whole latex B- and C- sera were shown to be largely ineffective against human B lymphocytes, of both cancer origin (BDCM) and non-cancer origin (Bristol 8); albeit slight dip in cell viability were discerned at high concentrations (>100mg/mL) of whole C-serum, the retentate of dialysed C-serum, the increment however was more prominant in the dialysed C-serum precipitate (DCP) compared to the dialysed C-serum supernatant (DCS). DCP also showed a marginally higher specificity against BDCM (LC50 = 55.95 Mg/mL) compared to Bristol 8 (LC50 = 75.62 Mg/mL). However in the treatments with the retentate of dialysed B-serum, both BDCM and Bristol 8 cells remained unaffected.
650			_aAnticancer
650			_aDialysis
650			_aLatex B-serum
650			_aLatex C-serum
650			_aMTS
650			_aSuspension cells
700			_aChai Y L
700			_aChow T W
700			_aOng M T
700			_aSunderasan E
700			_aYang K L
942			_cJS
999			_c70058 _d70058