Graft compatibility were investigated for 70 Hevea clones combinations. The combination of graftings on rubber trees used in this study (1) as a scion PB 260 combination with rootstocks BPM1, PR255, LCB1320, PR300, AVROS2037, RRIM712; (2) as a scion PR255, PR261, BPM1, BPM24, RRIC100, RRIC101, RRIC102, RRIC110, RRIM712 and PB260 combination with rootstocks BPM1, BPM24, RRIC100, RRIC101, RRIC102 and RRIC110 respectively, and as a control were scio/rootstock from the same clone and GT1/GT1 as a standard clone. The protein of the various samples of scion latex protein were analyzed by SDS-PAGE from every grafting combination. The alteration of protein banding pattern determined based on the presence or absence of the same bands of protein among plants. The results showed remarkable variations in the latex protein banding patterns of scion with high genetic distances from the rootstock clone. The variations noticed in the protein patterns among the budded plants of the same clone may be due to the stock scion interaction. Polymorphism were founded especially fom protein with low molecular weight i.e. 29-45 kD. These protein generally produced under stress condition. The mechanism of graft-induced changes of the protein metabolism in scion affected by rubber rootstock remains obscure. The possibility of foreign gene transport from stock to scion through the vascular system, integration into genome and its correlation with genetic similarity is being pursued at molecular level.