A small-scale clone trial (SSCT) comparing 50 Hevea brasiliensis Wickham clones was established in June 2008 in the Chup experimental plantation of the Cambodian Rubber Research Institute (CRRI), Tboung Khmum Province, Cambodia. Planting design was the standard recommended by CRRI (6m x 3m, 555 trees/ha). The experiment was set up as a Randomised Complete Block Design (RCBD), with 4 replications of 13 planted trees (elementary plots of 1 row x 13 planted trees on this row), giving a total of 52 initially planted trees per clone. Tappable trees (circumference at least equal to 50 cm when measured at 1 m from the ground, as per CRRI opening recommendations) were opened for tapping in June 2016, at the height of 1.30 m from the ground, and tapped on panel BO-1 in years 2016/17 (year 1, BO-1/1), 2017/18 (year 2, BO-1/2) and 2018/19 (year 3, BO-1/3). The tapping system was S/2 d3 7d/7 nil stim (without any ethephon stimulation), with a tapping cut angle of 30o and without rain guarding, revealing the latex yield due to tapping only. The first measurement of the main latex physiological parameters (Sucrose, Inorganic Phosphorus and Thiols) was performed on panel BO-1/3 during the 3rd year of tapping, in October 2018. This latex physiological assessment allowed to set up a first clonal latex metabolic typology (latex metabolism and latex sugar loading) of those 50 clones under the particular climate and soil conditions of the historic planting area of Tbong Khmum and Kampong Cham in Cambodia. It confirmed the physiological clonal characteristics known in other areas, especially in Western Africa, but also showed some differences. This clonal typology will be especially useful to help in setting up the clonal planting recommendations and to optimise the stimulation recommendations for these 50 clones under the particular ecoclimatic conditions of these two provinces of Cambodia.