The slip casting of ceramics uses synthetically prepared water-soluble polymers and polymer emulsions as binder to achieve adequate yield stress of the consolidated body and high green strength. Substitution of synthetically prepared binders with a naturally renewable one is highly recommended for environmental friendliness and sustainability. Herein, slip casting of aqueous alumina slurries using natural rubber latex (NRL) binder is studied for the first time. Slurries of high alumina loading (40–55 vol%) at rubber concentrations in the range of 2–8 wt% obtained by mixing a concentrated aqueous alumina powder dispersion and a concentrated NRL exhibit viscosity and yield stress suitable for slip casting. The thickness of the body produced in 1 h from the slurries containing the NRL binder by slip casting in a plaster of Paris mold is three times higher than that produced from a slurry prepared using 2 wt% polyvinyl alcohol (PVA) binder. The slip-cast green bodies after annealing at 200 °C show high strength (3–9.68 MPa) due to cross-linking of rubber. Sintered ceramics prepared from the slip-cast bodies exhibit ~ 97% theoretical density (T.D) with an average grain size of 1.8 μm. NRL binder-based slip casting is capable of producing sintered alumina crucibles of wall thickness as low as 1.2 mm. NRL can be an eco-friendly and sustainable candidate binder for the slip casting of ceramic materials.