In this study, an attempt was made to reduce the incompatibility between silica and natural rubber by coating the silica particles with the non-rubber constituents present in natural rubber latex serum. The presence of various non rubber constituents like proteins, carbohydrates and lipids on silica surface were confirmed from TGA, UV nad FTIR spectroscopy. RPA studies showed improved processability and cure characteristics for composite prepared from coated silica compared to the unmodified silica. The Payne effect studies of uncures compound showed that the filler-filler interaction ( ) decreased by 70 per cent than the control at 2 per cent serum coating on silica. The better processability of the modified rubber-silica compound is further evident from the lowering of the elastic torque and minimum rheometric torque (ML) of the respective vulcanizates. The serum modification on silica reduced the viscous shear modulus (G) and loss factor (tan ) by 36 and 33 per cent respectively, compared to the control. The physical properties of the coated system were comparable with that of the control compound.