Cylindrocladium quinqueseptatum causes leaf fall of clove in Sri Lanka and is responsible for the leaf spots of rubber in Malaysia. Only one isolate (Kp) from four pathogenic isolates examined secreted polygalacturanase (PG) when grown in liquid media. None of the isolates secreted pectin lyase (PL). The extracts of clove and rubber leaf tissues, inoculated with the Kp isolate did not show any PG and PL activity. The leaf tissue did not have the ability to inhibit C.quinqueseptatum PG produced in culture. All isolates of C.quinqueseptatum secreted cellulases viz. cellobiase and B-glucosidase in culture. Cellobiase was detected in the inoculated rubber leaves. The leaves of B-glucosidase, an inherent enzyme of Hevea leaves, also increased rapidly following infection. The results indicate that pectic enzymes play a minimal or no role in disease development of C.quinqueseptatum infection in cloves and Hevea. Thus cellulolytic enzyme probably play a nutritive role.