Genetic tansformation of Hevea brasiliensis with hman arial ntriuretic Factor (Record no. 59861)

MARC details
000 -LEADER
fixed length control field 01659nam a2200217Ia 4500
100 ## - MAIN ENTRY--AUTHOR NAME
Personal name Sunderasan E
245 #0 - TITLE STATEMENT
Title Genetic tansformation of Hevea brasiliensis with hman arial ntriuretic Factor
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Name of publisher Journal of Rubber Research
Year of publication 2012
300 ## - PHYSICAL DESCRIPTION
Number of Pages 255-264
520 ## - SUMMARY, ETC.
Summary, etc Agrobacterium mediated genetic transformation was performed on anther callus of Hevea cultivar GLI with a gene encoding human atrial natriuretic factor (HANF), a peptide hormone that is involved in regulating cardiac blood pressure. The gene constructs containing four different lengths of the indigenous hevein promoter, also incorporated the marker nptII for selection of transformants. Thus far 28 plants were regenerated and their bud-grafted generations were successfully transferred to the soil; all transcript in leaf samples was detected by RT-PCR in a number of original transformants and their vegetative generations, and the authenticity of the amplicon was confirmed by nucleotide sequencing. Polyclonal anti-atrial natriuretic peptide detected a band in the low molecular weigh region in western- immunoblot of leave protein of an original transformed plant, while MALDITOF-TOF and database searches of the corresponding protein band on SDS-gel revealed matches to atrial natriuretic peptide in the C-terminus of HANF.
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical Term genetic transformation
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Topical Term Hevea brasiliensis
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Topical Term human atrial natriuretic factor
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Topical Term protein mass-spectra analysis
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Topical Term RT-PCR
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Arokiaraj P
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Azharuddin Azlina
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Badaruddin EBadrul
942 ## - ADDED ENTRY ELEMENTS (KOHA)
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